COMPANY

TARGETED APPROACH TO CIPN

Cool Flame Bio is developing a synthetic peptide platform CFB-001. It is designed to protect mitochondrial structure and function in sensory neurons and protect these neurons from chemotherapy induced damage.

DIFFERENTIATED BIOLOGY

Focused on mitochondrial protection/ stabilization central to peripheral nerve injury and neuropathic pain. A platform for multiple peripheral neuropathies based on mitochondrial dysfunction including CIPN, and other Neuropathies like Diabetic, Radiation, and Compression.

ONCOLOGY-COMPATIBLE

Designed to preserve the anti‑cancer activity of standard chemotherapies while reducing neurotoxicity. Allows patients to complete their full chemotherapy regimen otherwise limited by CIPN intolerance.

CLEAR REGULATORY PATH

Potential for accelerated development based on clinical need, lack of treatment alternatives, and validated clinical endpoints.

Report abuse